Statins inhibit lymphocyte homing to peripheral lymph nodes
نویسندگان
چکیده
منابع مشابه
Molecular Mechanisms of Lymphocyte Homing to Peripheral Lymph Nodes
To characterize the adhesion cascade that directs lymphocyte homing to peripheral lymph nodes (PLNs), we investigated the molecular mechanisms of lymphocyte interactions with the microvasculature of subiliac lymph nodes. We found that endogenous white blood cells and adoptively transferred lymph node lymphocytes (LNCs) tethered and rolled in postcapillary high endothelial venules (HEVs) and to ...
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The tissue localization or "homing" of circulating lymphocytes is directed in part by specialized vessels that define sites of lymphocyte exit from the blood. In peripheral lymph nodes, mucosal lymphoid tissues (Peyer's patches and appendix), and sites of chronic inflammation, for example, lymphocytes leave the blood by adhering to and migrating between those endothelial cells lining postcapill...
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ژورنال
عنوان ژورنال: Immunology
سال: 2007
ISSN: 0019-2805,1365-2567
DOI: 10.1111/j.1365-2567.2006.02505.x